The present study was carried out to evaluate the analgesic activity of Jussiaea hyssopifolia plant in adult Swiss albino mice.weighing around 25-30gm. Methanolic extract of dried plant Jussiaea hyssopifolia at a rate of 200, 300mg/kg body weight were used in the present study. The study was conducted as per hot plate method. Methanolic extract of Jussiaea hyssopifolia showed significant effect when compared to standard drug diclofenac. The extract at 200mg/kg showed significant activity (P<0.01). Methanolic extract showed significant activity at tested dose levels after 45 minute interval. The result showed significant analgesic activity against stimuli. This is evidenced by significant increase in the reaction time by thermal stimuli.
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